About
Dr. Alhamad joined the Erbay Lab in 2026 as a Postdoctoral Scholar.
Education and Degree(s)
- Ph.D. in Cellular Biology and Anatomy (Augusta University, USA), 2025
- Masters in Pharmaceutical Sciences with a concentration in Pharmacology (University of
Sharjah, UAE), 2021 - Bachelor of Pharmacy (University of Sharjah, UAE), 2018
Publications
- Alhamad, D.W., Bensreti, H., Ding, K., Sultana, S., Yearwood, C.L., Ellingwood, A.,
Shaver, J., Burkhart, K., Tripathi, A., Dorn, J., Cushing, M., Nesbit, H., Dai, C., Morey, E.,
Gross, C., Alhamad, M., Taylor, D., Cherezova, A., Ilatovskaya, D.V., Zhi, W., Cooley, M.,
Zhong, R., Johnson, M.H., Bollag, W.B., Hamrick, M.W., Fulzele, S., Hill, W.D., Isales,
C.M., McGee-Lawrence, M.E. (2026). Tryptophan metabolites 3-hydroxykynurenine
(3HK) and 3-hydroxyanthranilic acid (3HAA) increase oxidative stress and impair
osteoblastic bone formation. Journal of Biological Chemistry. Accepted. - Tripathi, A., Sultana, S., Vyavahare, S., Chen, J., Paul, A., Shi, H., Zhi, W., Pacholczyk,
R., Mendhe, B., Anand, A., Carrillo, A., Lindsay, J., Alhamad, D.W., Bensreti, H.,
Yearwood, C.L., Taylor, D., Gross, C., Johnson, M., Belin de Chantemele, E.J., Hamrick,
M.W., McGee-Lawrence, M.E. (2025). The antiretroviral drug emtricitabine increases
kynurenine: tryptophan ratio, aryl hydrocarbon receptor activation, and cellular
senescence in female mice. Biochimie. - Weaver, S.R., Doolittle, M.L., Durdan, M.M., Narum, A.K., Weivoda, M.M., Alhamad,
D.W., McGee-Lawrence, M.E., Khosla, S., Taylor, E.L., Bradley, E.W., de Velasco,
E.M.F., Wickman, K., Westendorf, J.J. (2025). Global but not myeloid lineage-directed
Girk3 deletion increases bone mass in female mice. JBMR Plus. - Yu, K., Vyavahare, S., Alhamad, D., Bensreti, H., Ruan, L., Tuladhar, A., Dai, C.,
Shaver, J.C., Tripathi, A., Ding, K., Pacholczyk, R., Cooley, M.A., Zhong, R., Johnson,
M.H., Chen, J., Bollag, W.B., Isales, C.M., Hill, W.D., Hamrick, M.W., Fulzele, S.,
McGee-Lawrence, M.E. (2025). Inhibition of AhR improves cortical bone and skeletal
muscle function via preservation of neuromuscular junctions. JCI Insight. - Dorn, J., Alhamad, D.W., Bensreti, H., Yearwood, C.L., Allen, T.J., Cushing, M., Shaver,
J.C., Gross, C., Whichard, W.C., Dai, C., Yu, K., Zhong, R., Cooley, M.A., Johnson,
M.H., Bollag, W.B., Fulzele, S., Isales, C.M., Hamrick, M.W., Hill, W.D., McGee-
Lawrence, M.E. (2025). Expression of the aryl hydrocarbon receptor in Osterix-lineage cells regulates adult skeletal homeostasis in a compartment-specific manner. JBMR Plus. - Hagan, M.L., Tuladhar, A., Yu, K., Alhamad, D.W., Bensreti, H., Dorn, J., Piedra, V.M.,
Cantu, N., Stokes, E.G., Blumenthal, D., Roberts, R.L., Balayan, V., Bass, S.M.,
Dickerson, T., Cartelle, A.L., Montesinos-Cartagena, M., Awad, M.E., Castro, A.A.,
Garland, T., Cooley, M.A., Johnson, M., Hamrick, M.W., McNeil, P.L., McGee-Lawrence,
M.E. (2024). Osteocyte Sptbn1 Deficiency Alters Cell Survival and Mechanotransduction
Following Formation of Plasma Membrane Disruptions (PMD) from Mechanical
Loading. Calcified Tissue International, 115(5), 725–743. - Tuladhar, A., Shaver, J.C., McGee, W.A., Yu, K., Dorn, J., Horne, J.L., Alhamad, D.W.,
Hagan, M.L., Cooley, M.A., Zhong, R., Bollag, W., Johnson, M., Hamrick, M.W., McGee-
Lawrence, M.E. (2024). Prkd1 regulates the formation and repair of plasma membrane
disruptions (PMD) in osteocytes. Bone, 186, 117147. - Sebastian, A., Abu Rabah, R.R., Zaraei, S.O., Vunnam, S., Sultan, S., Anbar, H.S., El-
Gamal, R., Tarazi, H., Sarg, N., Alhamad, D.W., Al Shamma, S.A., Shahin, A.I., Omar,
H.A., Al-Tel, T.H., El-Gamal, M.I. (2024). Design, synthesis, biological evaluation, and in
silico studies of novel pyridopyridine derivatives as anticancer candidates targeting FMS
kinase. European Journal of Medicinal Chemistry, 274, 116557. - Elgendy, S.M., Zaher, D.M., Sarg, N.H., Abu Jayab, N.N., Alhamad, D.W., Al-Tel, T.H.,
Omar, H.A. (2024). Autophagy Inhibition Potentiates Energy Restriction-Induced Cell
Death in Hepatocellular Carcinoma Cells. IUBMB Life. - Bensreti, H., Yu, K., Alhamad, D.W., Shaver, J., Kaiser, H., Zhong, R., Whichard, C.W.,
Parker, E., Grater, L., Faith, H., Johnson, M., Cooley, M.A., Fulzele, S., Hill, W.D., Isales,
C.M., Hamrick, M.W., McGee-Lawrence, M.E. (2023). Orchiectomy sensitizes cortical
bone in male mice to the harmful effects of kynurenine. Bone, 173, 116811. - Bensreti, H., Alhamad, D.W., Gonzalez, A.M., Pizarro-Mondesir, M., Bollag, W.B.,
Isales, C.M., McGee-Lawrence, M.E. (2023). Update on the Role of Glucocorticoid
Signaling in Osteoblasts and Bone Marrow Adipocytes During Aging. Current
Osteoporosis Reports, 21(1), 32–44. - Alhamad, D.W., Bensreti, H., Dorn, J., Hill, W.D., Hamrick, M.W., McGee-Lawrence,
M.E. (2022). Aryl hydrocarbon receptor (AhR)-mediated signaling as a critical regulator
of skeletal cell biology. Journal of Molecular Endocrinology, 69(3), R109–R124. - Alhamad, D.W., Elgendy, S.M., Hersi, F., El-Seedi, H.R., Omar, H.A. (2022). The
inhibition of autophagy by spautin boosts the anticancer activity of fingolimod in
multidrug-resistant hepatocellular carcinoma. Life Sciences, 304, 120699. - Alhamad, D.W., Elgendy, S.M., Al-Tel, T.H., Omar, H.A. (2021). Tangeretin as an
adjuvant and chemotherapeutic sensitizer against various types of cancers: a
comparative overview. Journal of Pharmacy and Pharmacology, 73(5), 601–610. - Khaiwa, N., Maarouf, N.R., Darwish, M.H., Alhamad, D.W., Sebastian, A., Hamad, M.,
Omar, H.A., Orive, G., Al-Tel, T.H. (2021). Camptothecin's journey from discovery to
WHO Essential Medicine: Fifty years of promise. European Journal of Medicinal
Chemistry, 223, 113639. - Alyammahi, S.K., Abdin, S.M., Alhamad, D.W., Elgendy, S.M., Altell, A.T., Omar, H.A.
(2021). The dynamic association between COVID-19 and chronic disorders: An updated
insight into prevalence, mechanisms and therapeutic modalities. Infection, Genetics and
Evolution, 87, 104647. - Elgendy, S.M., Alyammahi, S.K., Alhamad, D.W., Abdin, S.M., Omar, H.A. (2020).
Ferroptosis: An emerging approach for targeting cancer stem cells and drug
resistance. Critical Reviews in Oncology/Hematology, 155, 103095. - Abdin, S.M., Elgendy, S.M., Alyammahi, S.K., Alhamad, D.W., Omar, H.A. (2020).
Tackling the cytokine storm in COVID-19, challenges and hopes. Life Sciences, 257,
118054. - Semreen, M.H., El-Gamal, M.I., Abdin, S., Alkhazraji, H., Kamal, L., Hammad, S., El-
Awady, F., Waleed, D., Kourbaj, L. (2018). Recent updates of marine antimicrobial
peptides. Saudi Pharmaceutical Journal, 26(3), 396–409.
Honors and Awards
- Selected for ASBMR Student Cohort Program, USA, 2022
- University of Sharjah research grant for a project titled “Mechanistic insight into
autophagy in drug-resistant hepatocellular carcinoma”, UAE, 2020 - Boehringer Ingelheim research grant for a project titled “Design, Synthesis and
Biological Evaluation of New Sulfonate Derivatives”, UAE, 2016 - Full M.Sc degree scholarship in Pharmaceutical Sciences, UAE, 2019
- Scientific excellence award, University of Sharjah, UAE, 2018